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The Kalamazoo River is a river in the U.S. state of Michigan. The river is 166 miles (267 km) long from the headwaters of the southern branch to Lake Michigan. The river's watershed drains an area of approximately 2,020 square miles (5,230 km²) and drains portions of eight counties in southwest Michigan: Allegan, Barry, Eaton, Van Buren, Kalamazoo, Calhoun, Jackson, Hillsdale, Kent and Ottawa. The river has a median flow of 1863 cubic feet per second (52.8 m³/s) at New Richmond, Michigan, upstream from its mouth at Saugatuck, Michigan.